Agglutination is

Agglutination is

• A. Bursting of red blood cells due to plasma not matching
• B. Dissolution of plasma
• C. Clotting of platelets
• D. Clumping of red blood cells due to antibodies

Answer: (D)

Agglutination is the clumping of red blood cells caused by antibodies binding to antigens on the cell surface and linking cells together. This is the reaction you look for in blood typing and transfusion crossmatching, where antibodies against foreign RBC antigens cause visible aggregates. The other descriptions refer to different processes: hemolysis is the rupture of red cells due to incompatibility, not just clumping; dissolution of plasma isn’t a standard RBC reaction; and platelet clotting is a coagulation process, not antibody-driven red cell agglutination.

Agglutination is the clumping of red blood cells caused by antibodies binding to antigens on the cell surface and linking cells together. This is the reaction you look for in blood typing and transfusion crossmatching, where antibodies against foreign RBC antigens cause visible aggregates. The other descriptions refer to different processes: hemolysis is the rupture of red cells due to incompatibility, not just clumping; dissolution of plasma isn’t a standard RBC reaction; and platelet clotting is a coagulation process, not antibody-driven red cell agglutination.